冠状动脉CTA中显示心包周围脂肪组织衰减的不同重建算法的差异

Yuxuan Zhu¹, Jiajie Zhu¹, Xin Ding¹

¹Department of Radiology, Nanjing BenQ Medical Center, The Affiliated BenQ Hospital of Nanjing Medical University, Nanjing, Jiangsu Province, China.

Scientific reports

|December 29, 2025

まとめ

冠状动脉炎的脂肪衰减指数（FAI) 根据冠状动脉CT血管造影（CCTA）重建算法的不同而有显著差异。标准化方案对于多中心研究中准确、可重现的FAI结果至关重要。

科学分野:

心血管画像診断
医用物理学
放射線学

背景:

脂肪減衰指数（FAI）は、冠状動脈CT血管造影（CCTA）で測定可能な冠状動脈炎症の感受性バイオマーカーである。
CCTAで使用される異なる画像再構成アルゴリズムは、FAI測定に影響を与える可能性がある。

主な方法:

患者は、冠状動脈プラークの存在（正常、プラークなし、非石灰化、混合、石灰化）に基づいて分類された。
FAI、心膜周囲脂肪組織の減衰、および画像ノイズを、冠状動脈全体にわたって各アルゴリズム（DLIR-H、ASiR-V50%、FBP）について測定した。
アルゴリズム間およびプラーク群間での測定値を比較するために統計分析を行った。

結論:

再構成アルゴリズムの選択は、CCTAにおけるFAI測定に大きく影響する。
多施設共同研究および縦断的研究では、再現可能で比較可能なFAI結果を保証するために、標準化された再構成プロトコルが不可欠である。

キーワード:

アルゴリズム冠状動脈CTA 脂肪減衰指数心臓

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