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Updated: Jun 19, 2026

Personalized Peptide Arrays for Detection of HLA Alloantibodies in Organ Transplantation
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新規HLA-Cアレル：HLA-C*06:02:01:107および-C*07:01:01:148の同定

María Rosa Moya-Quiles1, Manuel Muro1

  • 1Immunology Service, Clinical University Hospital Virgen de la Arrixaca (HCUVA)-Biomedical Research Institute of Murcia (IMIB), Murcia, Spain.

HLA
|December 30, 2025
PubMed

キーワード:
HLA-C*06:02:01:107HLA-C*07:01:01:148新規アレル次世代シーケンシング

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Blood Types02:20

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Human blood is classified into different types based on the presence of antigens on the red blood cell's surface and antibodies in the plasma. Proper identification of blood type is essential for successful blood transfusion. The International Society of Blood Transfusion has identified 38 human blood types based on the surface antigens on the red blood cells. The most common types are ABO, Rh, and MNS blood types.
ABO blood group
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Genome-wide association studies or GWAS are used to identify whether common SNPs are associated with certain diseases. Suppose specific SNPs are more frequently observed in individuals with a particular disease than those without the disease. In that case, those SNPs are said to be associated with the disease. Chi-square analysis is performed to check the probability of the allele likely to be associated with the disease.
GWAS does not require the identification of the target gene involved in...