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Updated: Jan 7, 2026

Bilateral Renal Ischemia-Reperfusion Model for Acute Kidney Injury in Mice

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慢性肝疾患における急性腎障害：横断研究における原因と有病率

Pankaj Kumar Gupta¹, Rahul Soni², Yasha Bandil³

¹Deprtment of General Medicine, Birsa Munda Government Medical College, Shahdol, Madhya Pradesh, India.

|December 30, 2025

Abstract:

Chronic liver disease (CLD) is a prevalent condition with significant systemic complications and acute kidney injury (AKI) is a common and serious complication that worsens prognosis. This prospective observational study, conducted from November 2019 to June 2021 at G.R. Medical College, Gwalior, included 100 CLD patients. The study found that 30% of patients developed AKI, with sepsis as the most common precipitating factor. Severe renal impairment (Stage 3 AKI) was present in 46.6% of AKI cases. Alcohol was the leading etiology of CLD and the timely diagnosis and management of AKI in CLD patients are essential to improving outcomes and reducing mortality.

キーワード:

慢性肝疾患急性腎障害アルコール性肝疾患肝硬変敗血症

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