クリプト原発性多発性潰瘍性狭窄性小腸炎（CMUSE）：稀な症例と文献レビュー

Cryptogenic multifocal ulcerative stenosing enteritis (CMUSE) is a rare enteropathy of unknown aetiology and pathophysiology. It is characterized by chronic and recurrent ulceration and stenosis of the small intestine. We present the case of a 33 year old female who had multiple presentations to our hospital with symptoms of small bowel obstruction. Diagnostic laparoscopy revealed extensive serosal adhesions with mixed transmural inflammation. The mucosa was extensively ulcerated and the bowel wall was congested and haemorrhagic, with hypertrophy of the muscularis propria. Ileoscopy revealed multiple strictures. Following treatment with balloon dilatation and surgical resection, she responded to treatment with immunomodulators and has remained in remission. CMUSE is a rare but important differential of benign SI strictures. The mainstays of treatment are steroids, immunomodulators, balloon dilatations, and surgical resection. Treatment should be aimed at reducing steroid dependence and preserving small bowel length, resorting to surgical resection in cases of occluding strictures.