難治性黄斑円孔閉鎖に対する硝子体腔内灌流液（BSS）注入法の改良法

Flavio Mac Cord Medina¹, Guilherme Thome De Carvalho, Bruno Vasconcelos Coimbra

¹Hospital Universitário Pedro Ernesto, Universidade do Estado do Rio de Janeiro, Rio de Janeiro, RJ, Brazil.

Retinal cases & brief reports

|December 30, 2025

要旨

Purpose:

To present a refined technique utilizing subretinal injection of Balanced Salt Solution (BSS) for the closure of refractory macular holes.

Methods:

This case report details a 70-year-old female patient with a refractory macular hole in the left eye, who underwent pars plana vitrectomy (PPV) combined with internal limiting membrane (ILM) peeling, gas tamponade, and subretinal injection of BSS.

Results:

One month postoperatively, optical coherence tomography (OCT) confirmed successful closure of the macular hole, with best-corrected visual acuity (BCVA) improving to 20/100 in the affected eye. At six-month follow-up, the macular hole remained closed, and OCT revealed partial restoration of the ellipsoid zone and external limiting membrane. BCVA was maintained at 20/100.

Conclusion:

Subretinal BSS injection appears to be an effective technique for closing refractory macular holes, offering a promising option for complex cases.

キーワード:

平衡塩溶液（BSS）求心性水圧移動難治性黄斑円孔硝子体下注入

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