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Updated: Jan 7, 2026

Practical Aspects of Sample Preparation and Setup of 1H R1ρ Relaxation Dispersion Experiments of RNA
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Practical Aspects of Sample Preparation and Setup of 1H R1ρ Relaxation Dispersion Experiments of RNA

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DNP強化マジック・アングル・スピニング・ソリッドステート・NMRスペクトロスコーピーは,RNA-リガンド相互作用を決定する

Alexey Sudakov1, Johanna Becker-Baldus2, Konstantin S Mineev1

  • 1Institute for Organic Chemistry and Chemical Biology, Center for Biomolecular Magnetic Resonance (BMRZ), Goethe University Frankfurt am Main, Max-von-Laue-Str. 7, Frankfurt 60438, Germany.

Journal of the American Chemical Society
|December 30, 2025
PubMed
まとめ

マジック・アングル・スピニング・ソリッドステート・NMR ダイナミック・ニュクリア・ポラライゼーション (MAS-DNP) は,大きなRNA-リガンド複合体における分子認識を明らかにする. 選択的ラベル付けはリボスイッチと薬物開発の構造的な洞察の鍵です.

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