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関連する概念動画

Olfaction01:25

Olfaction

48.0K
The sense of smell is achieved through the activities of the olfactory system. It starts when an airborne odorant enters the nasal cavity and reaches olfactory epithelium (OE). The OE is protected by a thin layer of mucus, which also serves the purpose of dissolving more complex compounds into simpler chemical odorants. The size of the OE and the density of sensory neurons varies among species; in humans, the OE is only about 9-10 cm2.
The olfactory receptors are embedded in the cilia of the...
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Physiology of Smell and Olfactory Pathway01:20

Physiology of Smell and Olfactory Pathway

12.1K
Humans detect odors with the help of specialized cells located in the upper part of the nasal cavity, called olfactory receptor neurons (ORNs). ORNs possess hair-like structures called cilia, which are receptive to sensations from the inhaled air. When an odorant molecule binds to a specific receptor on the cell of the cilia, it leads to a series of events that ultimately cause the ORN to send electrical signals to the olfactory bulb in the brain through the olfactory nerves.
The olfactory...
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Olfactory Receptors: Location and Structure01:03

Olfactory Receptors: Location and Structure

11.1K
The process of olfaction, also known as the sense of smell, is a sophisticated chemical response system. The specialized sensory neurons that facilitate this process, known as olfactory receptor neurons, are situated in an upper segment of the nasal cavity, known as the olfactory epithelium. Olfactory sensory neurons are bipolar, with their dendrites extending from the epithelium's apex into the mucus that lines the nasal cavity. Airborne molecules, when inhaled, traverse the olfactory...
11.1K
Motor and Sensory Areas of the Cortex01:14

Motor and Sensory Areas of the Cortex

6.8K
The cerebral cortex, the brain's outermost layer, is pivotal in processing complex cognitive tasks, emotions, and various sensory inputs and executing voluntary motor activities. This intricate structure is divided into three primary functional areas: the motor areas, sensory areas, and association areas.
Motor Areas
The motor areas located in the frontal lobe are central to controlling voluntary movements. This region is further subdivided into the primary motor cortex and the premotor cortex....
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Somatosensory, Motor, and Association Cortex01:23

Somatosensory, Motor, and Association Cortex

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The somatosensory cortex in the parietal lobes is crucial for interpreting sensory data such as touch, temperature, and proprioception. The somatosensory cortex, situated in the parietal lobes, plays a vital role in interpreting sensory information like touch, temperature, and proprioception—awareness of body position. This specialized brain region features an organized structure wherein neurons at the top primarily process sensations originating from the lower body. In contrast, those at...
2.1K
Association Areas of the Cortex01:21

Association Areas of the Cortex

8.7K
Association areas are regions of the cerebral cortex that do not have a specific sensory or motor function. Instead, they integrate and interpret information from various sources to enable higher cognitive processes such as memory, learning, and decision-making. Some key association areas include the following:
Prefrontal Association Area: This area is located in the frontal lobe and is involved in planning, decision-making, and moderating social behavior. It connects with primary motor areas,...
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関連する実験動画

Updated: Jan 7, 2026

Imaging Odor-Evoked Activities in the Mouse Olfactory Bulb using Optical Reflectance and Autofluorescence Signals
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Published on: October 31, 2011

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嗅皮質の匂い情報の投影特異的ルーティング

Simon Daste, Tuan H Pham, Max Seppo

    bioRxiv : the preprint server for biology
    |December 31, 2025
    PubMed
    まとめ

    哺乳類皮質の情報ルーティングが解明された。逆行性ニューロン(嗅球投射)は早期に匂いの同一性をエンコードし、順行性ニューロン(内側前頭前野投射)は後でエンコードし、異なる可塑性を示す。

    キーワード:
    嗅皮質匂い情報ニューロン可塑性神経回路感覚処理

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    Quadruple Immunostaining of the Olfactory Bulb for Visualization of Olfactory Sensory Axon Molecular Identity Codes
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    関連する実験動画

    Last Updated: Jan 7, 2026

    Imaging Odor-Evoked Activities in the Mouse Olfactory Bulb using Optical Reflectance and Autofluorescence Signals
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    科学分野:

    • 神経科学
    • 感覚処理
    • 嗅皮質研究

    背景:

    • 哺乳類皮質感覚処理は、複雑な順行性および逆行性結合を含む。
    • これらの神経経路に沿った情報の正確なルーティングは、まだよく理解されていない。

    研究 の 目的:

    • マウス嗅皮質における逆行性および順行性ニューロンの機能的特性を調査すること。
    • 匂い情報がどのように処理され、異なる皮質経路を介してルーティングされるかを理解すること。

    主な方法:

    • 嗅球(逆行性)および内側前頭前野(順行性)に投射するニューロンの選択的標識。
    • 受動的な匂い曝露および匂い識別学習課題中のニューロン活動の記録。

    主要な成果:

    • 嗅球投射ニューロンは、匂い曝露の早期に匂いの同一性と報酬関連性をエンコードした。
    • 内側前頭前野投射ニューロンは、行動反応と相関して、これらの情報を後でエンコードした。
    • 内側前頭前野投射ニューロンは安定した価数表現を示した一方、嗅球投射ニューロンは有意な可塑性を示した。

    結論:

    • 匂い情報は、嗅皮質内の異なる順行性および逆行性経路を介して選択的にルーティングされる。
    • 嗅皮質ニューロンの機能的特性は、標的脳領域の計算要件に適応している。