デジタルツインパラダイムにおける糖尿病予測と管理
David B Olawade1, Rita Chikeru Owhonda2, John Oluwatosin Alabi3
1Department of Allied and Public Health, School of Health, Sport and Bioscience, University of East London, London, United Kingdom; Department of Research and Innovation, Medway NHS Foundation Trust, Gillingham ME7 5NY, United Kingdom; Department of Business, Management and Health, York St John University, London E14 2BA, United Kingdom.
Diabetes research and clinical practice
|December 31, 2025
まとめ
デジタルツイン技術は、仮想的な患者レプリカを作成することにより、積極的な糖尿病管理に有望な可能性を提供します。広範な臨床応用と糖尿病ケアにおける公平な適用には、さらなる検証が必要です。
科学分野:
- デジタルヘルス
- 計算モデリング
- 精密医療
背景:
- 従来の糖尿病管理は受動的であり、管理不良や合併症につながります。
- デジタルツイン(DT)技術は、仮想レプリカを通じて積極的で個別化されたアプローチを提供します。
- 糖尿病における現在のDTアプリケーションには、さらなる臨床的検証と実現可能性評価が必要です。
研究 の 目的:
- 糖尿病予測と管理におけるデジタルツイン技術の現在の応用をレビューすること。
- 糖尿病ケアにおけるDTの課題と将来の可能性を検討すること。
- 血糖値予測、インスリン投与量、合併症リスクにおけるDTの役割に関するエビデンスを統合すること。
主な方法:
- PubMed、Scopus、Web of Science、IEEE Xplore(2015-2024)を対象とした包括的な文献検索。
- 糖尿病、予測モデリング、治療最適化におけるDTに関する査読付き論文のクリティカルシンセシス。
- 方法論的アプローチ、パフォーマンスメトリック、実装上の課題の比較。
主要な成果:
- デジタルツインは、血糖値予測、個別化インスリン投与量、食事最適化、合併症リスク評価において可能性を示しています。
- 連続血糖測定、ウェアラブルセンサー、機械学習アルゴリズムの統合により、DTの能力が向上します。
- エビデンスの質は様々であり、ほとんどの研究は概念実証またはパイロット実装です。
結論:
- デジタルツイン技術は、精密糖尿病ケアのための進化するパラダイムです。
- 実装には、データプライバシー、検証要件、統合の複雑性への対処が不可欠です。
- 長期的な有効性、アルゴリズムバイアスの軽減、一般化可能性については、公平な採用のためにさらなる調査が必要です。
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