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Updated: Jan 7, 2026

Studying the Effects of Tumor-Secreted Paracrine Ligands on Macrophage Activation using Co-Culture with Permeable Membrane Supports
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Studying the Effects of Tumor-Secreted Paracrine Ligands on Macrophage Activation using Co-Culture with Permeable Membrane Supports

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腫瘍に関連したマクロファージのLIPA駆動による再プログラムが,骨肉腫における免疫抑制微環境を形成する

Zehao Guo1, Yutong Zou1, Yan Liao1

  • 1Department of Musculoskeletal Oncology, The First Affiliated Hospital of Sun Yat-sen University, Guangzhou, Guangdong, China; Guangdong Provincial Key Laboratory of Orthopedics and Traumatology, Guangzhou, Guangdong, China.

International immunopharmacology
|January 1, 2026
PubMed
まとめ

No abstract available in PubMed .

キーワード:
LIPA についてオステオサルコマTAM についてトリグリセリドの代謝腫瘍の微小環境

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The Tumor Microenvironment02:17

The Tumor Microenvironment

Every normal cell or tissue is embedded in a complex local environment called stroma, consisting of different cell types, a basal membrane, and blood vessels. As normal cells mutate and develop into cancer cells, their local environment also changes to allow cancer progression. The tumor microenvironment (TME) consists of a complex cellular matrix of stromal cells and the developing tumor. The cross-talk between cancer cells and surrounding stromal cells is critical to disrupt normal tissue...
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