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研究分野生物医学と臨床科学医学微生物学医療用感染剤 (プリオンを含む)
研究分野
生物医学と臨床科学
医学微生物学
医療用感染剤 (プリオンを含む)
ブチロラクトールAは,薬剤耐性菌におけるフリッパース阻害によってカスポファンギンの有効性を高めます.

ブチロラクトールAは,薬剤耐性菌におけるフリッパース阻害によってカスポファンギンの有効性を高めます.

Xuefei Chen ¹, H Diessel Duan ², Michael J Hoy ³, Kalinka Koteva ¹, Michaela Spitzer ¹, Allison K Guitor ¹, Emily Puumala ⁴, Aline A Fiebig ¹, Guanggan Hu ⁵, Bonnie Yiu ⁴, Sommer Chou ¹, Zhuyun Bian ³, Yeseul Choi ³, Amelia Bing Ya Guo ¹, Wenliang Wang ¹, Sheng Sun ³, Nicole Robbins ⁴, Anna Floyd Averette ³, Michael A Cook ¹, Ray Truant ⁶, Lesley T MacNeil ⁷, Eric D Brown ¹, James W Kronstad ⁵, Brian K Coombes ¹, Leah E Cowen ⁴, Joseph Heitman ³, Huilin Li ², Gerard D Wright ¹

Xuefei Chen ¹, H Diessel Duan ², Michael J Hoy ³

¹David Braley Centre for Antibiotics Discovery, M.G. DeGroote Institute for Infectious Disease Research, Department of Biochemistry and Biomedical Sciences, McMaster University, Hamilton, ON L8S 4K1, Canada.
²Department of Structural Biology, Van Andel Institute, Grand Rapids, MI 49503, USA.
³Department of Molecular Genetics and Microbiology, Duke University, Duke University Medical Center, Durham, NC 27710, USA.
⁴Department of Molecular Genetics, University of Toronto, Toronto, ON M5G 1M1, Canada.
⁵Michael Smith Laboratories, Department of Microbiology and Immunology, University of British Columbia, Vancouver, BC, Canada.
⁶Department of Biochemistry and Biomedical Sciences, McMaster University, Hamilton, ON L8S 4L8, Canada.
⁷David Braley Centre for Antibiotics Discovery, M.G. DeGroote Institute for Infectious Disease Research, Department of Biochemistry and Biomedical Sciences, McMaster University, Hamilton, ON L8S 4K1, Canada; Department of Biochemistry and Biomedical Sciences, McMaster University, Hamilton, ON L8S 4L8, Canada.

⁰David Braley Centre for Antibiotics Discovery, M.G. DeGroote Institute for Infectious Disease Research, Department of Biochemistry and Biomedical Sciences, McMaster University, Hamilton, ON L8S 4K1, Canada.

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2026年1月1日

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2026年1月1日

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Automation of Bio-Atomic Force Microscope Measurements on Hundreds of <em>C. albicans</em> Cells

Automation of Bio-Atomic Force Microscope Measurements on Hundreds of C. albicans Cells

Published on: April 2, 2021

Small-Scale Plasma Membrane Preparation for the Analysis of <em>Candida albicans</em> Cdr1-mGFPHis

Small-Scale Plasma Membrane Preparation for the Analysis of Candida albicans Cdr1-mGFPHis

Published on: June 13, 2021

Inhibition of <em>Aspergillus flavus</em> Growth and Aflatoxin Production in Transgenic Maize Expressing the α-amylase Inhibitor from <em>Lablab purpureus</em> L.

Inhibition of Aspergillus flavus Growth and Aflatoxin Production in Transgenic Maize Expressing the α-amylase Inhibitor from Lablab purpureus L.

Published on: February 15, 2019

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まとめ

No abstract available on PubMed

キーワード:

Apt1-Cdc50 についてカンジダ・オーリスクリプトコッカス抗真菌剤バチロラクトールA エキノカンディンフリップフェーズキノコ耐性自然産物シナジー

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Contact us これらのビデオが関連しない場合は

Automation of Bio-Atomic Force Microscope Measurements on Hundreds of <em>C. albicans</em> Cells

Automation of Bio-Atomic Force Microscope Measurements on Hundreds of C. albicans Cells

Published on: April 2, 2021

Small-Scale Plasma Membrane Preparation for the Analysis of <em>Candida albicans</em> Cdr1-mGFPHis

Small-Scale Plasma Membrane Preparation for the Analysis of Candida albicans Cdr1-mGFPHis

Published on: June 13, 2021

Inhibition of <em>Aspergillus flavus</em> Growth and Aflatoxin Production in Transgenic Maize Expressing the α-amylase Inhibitor from <em>Lablab purpureus</em> L.

Inhibition of Aspergillus flavus Growth and Aflatoxin Production in Transgenic Maize Expressing the α-amylase Inhibitor from Lablab purpureus L.

Published on: February 15, 2019

See all related videos

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Combined Effects of Drugs: Synergism

Combined Effects of Drugs: Synergism

Synergism is a useful mechanism where combining two or more drugs is more effective than each constituent used alone. Such combinations are also called supra-additive interactions. The drugs collectively enhance the final therapeutic effect by acting on different targets. Another advantage is that the low dose of each constituent drug is sufficient to achieve the desired effect. This helps reduce the duration of therapy and lower the adverse effects of these drugs.
Such synergistic combinations...

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