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基礎細胞がんにおけるヘッジホッグシグナル伝達活動の検出のための最適化された全マウントX-ガール染色:免疫分析と空間的統合のためのプラットフォーム

Hao Wang1, Yucui Zhu1, Arianna L Kim2

  • 1Department of Dermatology, Columbia University Irving Medical Center, New York, NY, USA.

Methods in molecular biology (Clifton, N.J.)
|January 1, 2026
PubMed
まとめ

No abstract available in PubMed .

キーワード:
基礎細胞がんエジホグ・パス免疫ミクロ環境ラックス・リポーター

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Hedgehog Signaling Pathway02:33

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The Hedgehog gene (Hh) was first discovered due to its control of the growth of disorganized, hair-like bristles phenotype in Drosophila, much like hedgehog spines. Hh plays a crucial role in the development of organs and the maintenance of homeostasis in both invertebrates and vertebrates. However, while Drosophila has only one Hh protein, mammals have multiple functional Hedgehog proteins - Sonic (Shh), Desert (Dhh), and Indian Hedgehog (Ihh). All of these homologous proteins have adapted to...