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Updated: Jan 7, 2026

Generation of a RIP1 Knockout U937 Cell Line Using the CRISPR-Cas9 System
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Generation of a RIP1 Knockout U937 Cell Line Using the CRISPR-Cas9 System

Published on: April 11, 2025

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CRISPR/Cas9ベースのゲノム編集を使用してIL17RBノックアウト細胞ラインの生成

Olivia Hu1, Alessandro Provvido1, Yan Zhu2

  • 1Department of Biological Sciences, St. John's University, Queens, NY, USA.

Methods in molecular biology (Clifton, N.J.)
|January 1, 2026
PubMed
まとめ

No abstract available in PubMed .

キーワード:
CRISPR/Cas9について遺伝子ノックアウトゲノム削除インタールイキン17受容体B

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The CRISPR-Cas system serves as a bacterial defense mechanism against invading genetic elements such as viruses and plasmids, forming the foundation for its adaptation as a powerful genome-editing tool. Originally discovered in prokaryotes, this system has been repurposed to revolutionize genetic engineering across a wide range of organisms, including plants, animals, and humans. The core component, Cas9, is an endonuclease derived from Streptococcus pyogenes, capable of introducing...
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