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Updated: Jan 7, 2026

Use of Single Chain MHC Technology to Investigate Co-agonism in Human CD8+ T Cell Activation
12:09

Use of Single Chain MHC Technology to Investigate Co-agonism in Human CD8+ T Cell Activation

Published on: February 28, 2019

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人間のデンドリット細胞におけるMGAT1ノックアウトは,CD8+ T細胞の活性化を促進する

Anne Louise Blomberg1, Betina Lyngfeldt Henriksen2, Weihua Tian1

  • 1Biotherapeutic Glycoengineering and Immunology, Section for Medical Biotechnology, Department of Biotechnology and Biomedicine, Technical University of Denmark, Kgs Lyngby, Denmark.

Frontiers in immunology
|January 2, 2026
PubMed
まとめ

No abstract available in PubMed .

キーワード:
CD8+ T細胞応答CRISPR/Cas9についてDCの差分化グライコエンジニアリングN-グリコシレーションデンドリック細胞 (DCs)

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Development and Functional Characterization of Murine Tolerogenic Dendritic Cells

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Tailoring In Vivo Cytotoxicity Assays to Study Immunodominance in Tumor-specific CD8+ T Cell Responses

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T Cell Activation and Clonal Selection01:22

T Cell Activation and Clonal Selection

T cells are integral to our adaptive immune system, recognizing and effectively responding to foreign antigens. T cell activation and clonal selection are pivotal in orchestrating this immune response. This article elucidates these mechanisms, detailing the roles of cluster of differentiation (CD) markers, major histocompatibility complex (MHC) molecules, costimulatory signals, and the process of clonal selection.
Naive T cells that have not yet encountered an antigen express two primary CD...
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