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Updated: Jan 7, 2026

RNA-seq Analysis of Transcriptomes in Thrombin-treated and Control Human Pulmonary Microvascular Endothelial Cells
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ベネズエラの馬頭炎ウイルスに感染したヒト内皮細胞のトランスクリプトミカルプロファイリングは,オマベロキソロン治療によるNRF2駆動の宿主再プログラムを示しています

Mostafa Rezapour1, Lorreta A Opoku2, Stephanie V Trefry2

  • 1Wake Forest Institute for Regenerative Medicine, Wake Forest University School of Medicine, Winston-Salem, NC, United States.

Frontiers in genetics
|January 2, 2026
PubMed
まとめ

No abstract available in PubMed .

キーワード:
Nrf2シグナリング概括された線形モデルで準確率と大きさ-高度スコア付け (GLMQL-MAS)ホスト指向療法オマベロクソロン (OMA)トランスクリプトミクスベネズエラ馬脳炎ウイルス (VEEV)

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Treatment for Pulmonary Arterial Hypertension: Endothelin Receptor Antagonists01:18

Treatment for Pulmonary Arterial Hypertension: Endothelin Receptor Antagonists

Endothelins (ETs) are potent vasoactive peptides critical in the human body's various physiological and pathological processes. One of the most promising therapeutic strategies for treating pulmonary arterial hypertension (PAH) involves counteracting the effects of these endothelins using a class of drugs known as endothelin receptor antagonists.
ETs are synthesized through a complex sequence of enzymatic steps, primarily involving an enzyme referred to as endothelin-converting enzyme...
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