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Updated: May 10, 2026

Isolation and Th17 Differentiation of Naïve CD4 T Lymphocytes
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Isolation and Th17 Differentiation of Naïve CD4 T Lymphocytes

Published on: September 26, 2013

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IMU-935によるRORγt- CBFβの相互作用の選択的妨害は,RORγtに依存するTh17の自己免疫を防ぐが,チモサイトの発達を妨げない

Hongmin Wu1, Xiancai Zhong1, Ning Ma2

  • 1Department of Immunology & Theranostics, Arthur Riggs Diabetes & Metabolism Research Institute.

The Journal of clinical investigation
|January 2, 2026
PubMed
まとめ

No abstract available in PubMed .

キーワード:
自己免疫疾患自己免疫性薬物療法免疫学

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関連する概念動画

T Cell Types and Functions01:24

T Cell Types and Functions

When T cells with CD4 markers are activated, they give rise to two types of effector cells: helper T cells and regulatory T cells. Meanwhile, T cells with CD8 markers differentiate into effector cytotoxic T cells. The differentiation of CD4 T cells into helper T cell subsets, such as Th1, Th2, and Th17 cells, is dependent on the antigen type, antigen-presenting cell, and regulatory cytokines.
Th1 cells stimulate dendritic cells to express necessary co-stimulatory molecules on their surfaces for...