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Alzheimer's Disease: Treatment01:22

Alzheimer's Disease: Treatment

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Alzheimer's Disease (AD), a neurodegenerative disorder, is pathologically identified by amyloid plaques and neurofibrillary tangles composed of tau protein. AD pharmacotherapy aims to manage cognitive symptoms, delay disease progression, and treat behavioral symptoms. The treatment is primarily symptomatic and palliative, with no definitive disease-modifying therapy available. Cholinesterase inhibitors, including donepezil (Aricept), rivastigmine (Exelon), and galantamine (Razadyne), are...
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Alzheimer's Disease: Overview01:26

Alzheimer's Disease: Overview

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Alzheimer's Disease (AD) is a continually advancing neurodegenerative disorder, distinguished by escalating memory loss, cognitive dysfunction, and dementia. The disease unfolds in three stages: preclinical, mild cognitive impairment (MCI), and dementia. Its onset is insidious, and the progression gradual, with the cause not well explained by other disorders.
The clinical diagnosis of AD hinges on the presence of memory and other cognitive impairments. Biomarkers, such as changes in Aβ...
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  2. Fgf22/fgfr2/yapは,アルツハイマー病における神経変性および認知障害を抑制するためにフェロプトーシスを調節する.
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  2. Fgf22/fgfr2/yapは,アルツハイマー病における神経変性および認知障害を抑制するためにフェロプトーシスを調節する.

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Assessing Iron Deposition in the Brains of 5xFAD Mice by Perls'/DAB Staining
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Assessing Iron Deposition in the Brains of 5xFAD Mice by Perls'/DAB Staining

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FGF22/FGFR2/YAPは,アルツハイマー病における神経変性および認知障害を抑制するためにフェロプトーシスを調節する.

Xiaoxiao Chen1, Hanbing Yao1, Shuqing Ma1

  • 1Wenzhou Medical University, Wenzhou, Zhejiang, China.

Experimental neurology
|January 2, 2026
まとめ

No abstract available in PubMed .

キーワード:
アルツハイマー病認知障害FGF22 についてフェロプトーシスニューロンアポトーシスYAP について

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