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MCAOラットモデルによる重要なmiRNAと脳卒中関連ネットワークの識別

Jiang Wu1, Yuying Yang2, Shan Yuan2

  • 1College of Coastal Agricultural Sciences, Guangdong Ocean University, Zhanjiang, Guangdong, 524088, China.

Biochemical and biophysical research communications
|January 3, 2026
PubMed
まとめ

No abstract available in PubMed .

キーワード:
発血性脳卒中MCAOラット脳卒中後の病理miRNA-mRNAネットワークmiRNA-seq について

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MicroRNA (miRNA) are short, regulatory RNA transcribed from introns—non-coding regions of a gene—or intergenic regions—stretches of DNA present between genes. Several processing steps are required to form biologically active, mature miRNA. The initial transcript, called primary miRNA (pri-mRNA), base-pairs with itself forming a stem-loop structure. Within the nucleus, an endonuclease enzyme, called Drosha, shortens the stem-loop structure into hairpin-shaped pre-miRNA. After...
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