関連する実験動画

Updated: May 6, 2026

Quantitative and Automated High-throughput Genome-wide RNAi Screens in C. elegans
10:58

Quantitative and Automated High-throughput Genome-wide RNAi Screens in C. elegans

Published on: February 27, 2012

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Caenorhabditis elegansのトランスクリプションファクターRNAiプラットフォームを使用して,ブロム化炎症阻害剤のインビオ高通量毒性スクリーニング

Siyeol Ahn1, Elizabeth Dufourcq Sekatcheff1, Jinhee Choi1

  • 1School of Environmental Engineering, University of Seoul, 163 Seoulsiripdae-ro, Dongdaemun-gu, Seoul 02504, Republic of Korea.

Toxicology
|January 3, 2026
PubMed
まとめ

No abstract available in PubMed .

キーワード:
不良結果の経路 (AOP)カエノラブディティス・エレガンス新しいアプローチの方法論 (NAM)RNA干渉 (RNAi)ブロミン製の阻燃剤

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Comprehensive Assessment of Germline Chemical Toxicity Using the Nematode Caenorhabditis elegans

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A High-throughput Assay for the Prediction of Chemical Toxicity by Automated Phenotypic Profiling of Caenorhabditis elegans

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関連する概念動画

RNA Interference01:23

RNA Interference

RNA interference (RNAi) is a process in which a small non-coding RNA molecule blocks the post-transcriptional expression of a gene by binding to its messenger RNA (mRNA) and preventing the protein from being translated.
This process occurs naturally in cells, often through the activity of genomically-encoded microRNAs. Researchers can take advantage of this mechanism by introducing synthetic RNAs to deactivate specific genes for research or therapeutic purposes. For example, RNAi could be used...
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Experimental RNAi02:15

Experimental RNAi

RNA interference (RNAi) is a cellular mechanism that inhibits gene expression by suppressing its transcription or activating the RNA degradation process. The mechanism was discovered by Andrew Fire and Craig Mello in 1998 in plants. Today, it is observed in almost all eukaryotes, including protozoa, flies, nematodes, insects, parasites, and mammals. This precise cellular mechanism of gene silencing has been developed into a technique that provides an efficient way to identify and determine the...
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