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Updated: Jan 7, 2026

Bile Duct Ligation in Mice: Induction of Inflammatory Liver Injury and Fibrosis by Obstructive Cholestasis
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C型肝炎の治癒後の線維症マーカー動態の臨床的影響:ペアビオプシーからの洞察

Hung-Wei Wang1, Hsueh-Chou Lai2, I-Ping Chiang3

  • 1School of Medicine, China Medical University, Taichung, Taiwan; Center for Digestive Medicine, Department of Internal Medicine, China Medical University Hospital, Taichung, Taiwan; Graduate Institute of Biomedical Sciences, China Medical University, Taichung, Taiwan.

Journal of the Formosan Medical Association = Taiwan yi zhi
|January 3, 2026
PubMed
まとめ

No abstract available in PubMed .

キーワード:
コラーゲンに比例する面積C型肝炎肝臓繊維症肝硬直の測定非侵襲性線維症マーカー持続したウイルス反応

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In clinical practice, the direct measurement of hepatic blood flow to evaluate liver function presents significant challenges due to the intricate and specialized nature of the necessary techniques. Consequently, healthcare professionals often rely on empirical estimates derived from thorough patient examinations and liver function tests to gauge liver health. Among the tools at their disposal, the Child–Pugh and MELD scoring systems stand out for their ability to categorize and assess...
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Chronic liver disease significantly impacts drug metabolism due to alterations in hepatic blood flow and enzyme accessibility. This disruption affects the body's pharmacokinetics—the movement and processing of drugs within the system. Key enzymes crucial for metabolizing medications become less accessible, changing how drugs are processed and utilized. Furthermore, liver disease influences the synthesis of plasma proteins, such as albumin and globulins, which play critical roles in drug...
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