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肝臓ステアトーシスの指標のための全ゲノムDNAメチル化パターン: 縦断的なマルチオーム研究

Jo Ciantar1, Sonja Rajić1, Daria Kostiniuk1

  • 1Molecular Epidemiology, Faculty of Medicine and Health Technology, Tampere University, Tampere, Finland.

Clinical epigenetics
|January 4, 2026
PubMed
まとめ

No abstract available in PubMed .

キーワード:
DNAメチル化脂肪肝指数GGT について縦軸代謝機能障害と関連した脂肪性肝疾患非アルコール性脂肪肝人口コホート

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Epigenetic changes alter the physical structure of the DNA without changing the genetic sequence and often regulate whether genes are turned on or off. This regulation ensures that each cell produces only proteins necessary for its function. For example, proteins that promote bone growth are not produced in muscle cells. Epigenetic mechanisms play an essential role in healthy development. Conversely, precisely regulated epigenetic mechanisms are disrupted in diseases like cancer.
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