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機械学習とマルチオミクス統合による高縮性心筋病におけるクプロプトーシス関連バイオマーカー候補者の特定

Weidong Wang1, Ye Tian2, Chunyu Wang3

  • 1Department of Ultrasound, The First Affiliated Hospital of Harbin Medical University, Harbin, 150001, China.

Applied biochemistry and biotechnology
|January 4, 2026
PubMed
まとめ

No abstract available in PubMed .

キーワード:
バイオマーカー候補クプロプトーシスハイパルトロフィック心筋病機械学習マルチオミックスの統合

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Hypertrophic cardiomyopathy, or HCM, is an autosomal dominant genetic disorder characterized by asymmetric left ventricular hypertrophy without ventricular dilation. It is more common in men and is typically diagnosed in young, athletic adults.EtiologyHCM is primarily genetic and is caused by mutations in genes encoding sarcomeric proteins. Researchers have identified over 1400 mutations across at least 11 different genes. Among these, the most frequently occurring mutations are found in the...
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