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非典型的血溶性および尿性症候群における補完剤の標的化:エキュリズマブとラヴリズマブの開発と現在の状態

Nicolas Maillard1, François Provot2

  • 1Hôpital Nord, St-Priest-en-Jarez, France

Nephrologie & therapeutique
|January 5, 2026
PubMed
まとめ

No abstract available in PubMed .

キーワード:
非典型的血解性尿性症候群血栓性微血管症エキュリズマブラヴリズマブ

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Complement System01:27

Complement System

The complement system is a group of approximately 20 plasma proteins that strengthen the body's defenses against infections through opsonization, inflammation, and cell lysis. Opsonization involves coating pathogens with complement proteins, making them more recognizable and facilitating phagocyte engulfment. Certain complement proteins induce inflammation that attracts immune cells to the site of infection. Cell lysis involves the destruction of pathogens through the formation of a...
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