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Lauren D Stettler1, Vincent T Kopysciansky1, Jenna E Poor1

  • 1Department of Chemistry, Susquehanna University, 514 University Avenue, Selinsgrove, Pennsylvania 17870, United States.

ACS omega
|January 5, 2026
PubMed
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No abstract available in PubMed .

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Protein synthesis is indispensable for viral replication, as viruses lack the cellular machinery required for this process and must hijack the host's translational apparatus. In response, host cells deploy a critical innate immune defense involving interferons, specialized cytokines that play a central role in inhibiting viral propagation.Upon viral detection, infected cells release interferons that bind to receptors on adjacent uninfected cells, activating the JAK-STAT signaling pathway and...