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Wei Zhao1, Meng Li2, Chuanqing Jia2

  • 1The Second Affiliated Hospital of Heilongjiang University of Chinese Medicine, Harbin, China.

Frontiers in pharmacology
|January 5, 2026
PubMed
まとめ

No abstract available in PubMed .

キーワード:
NF-κBとPPARγの信号伝達経路ネペタ ネットワーク分析RAW264.7 セルラインディテルペンリポポリサカリド誘発性炎症

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Neurokinin 1 (NK1) receptors are distributed across the GI tract, vagal afferents, and key CNS regions including the central vomiting center and chemoreceptor trigger zone (CTZ) Chemotherapy agents stimulate enterochromaffin cells in the gastrointestinal (GI) tract to release large amounts of substance P (SP). SP is a neuropeptide released by specific sensory nerves in response to many different stressors, including those in the GI mucosa affected by chemotherapy.  SP binds and activates...
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