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Updated: May 12, 2026

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Kenta Onishi1, Rika Sasaki1, Koki Hirota1

  • 1Department of Anesthesiology, Faculty of Medicine, University of Toyama, Toyama, Japan.

Frontiers in pharmacology
|January 5, 2026
PubMed
まとめ

No abstract available in PubMed .

キーワード:
GABAergic 阻害についてデスフルラン環境の豊かさ一般麻酔薬ヒッポカンプスプロポポール

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CNS Depressants: Alcohol and Nicotine

Ethanol, a clear colorless alcohol, has been consumed by humans for millennia, but its effects on the body are far from benign. At lower doses, it induces decreased inhibitions and loquaciousness, leading to its social appeal. However, it can cause severe consequences at higher doses, such as coma and respiratory depression, due to its zero-order elimination kinetics. Chronic ethanol abuse wreaks havoc on multiple organ systems, particularly the CNS and the liver. Abrupt cessation of ethanol...