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高度弱化したIL-18をPD-1にターゲティングして,抗腫瘍活性を増強する

Xueyuan Zhou1, Felix Klaus Geyer2, Jeffrey Takimoto1

  • 1Drug Discovery and Development, Fuse Biotherapeutics, Woburn, MA, United States.

Frontiers in immunology
|January 5, 2026
PubMed
まとめ

No abstract available in PubMed .

キーワード:
IL-18 についてPD-1 についてチェックポイント阻害剤サイトカイン免疫サイトカイン

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Tumor Immunotherapy01:27

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Immunotherapy is a treatment that boosts or manipulates the immune system to fight diseases, including cancer. For instance, by stimulating an immune response through vaccinations against viruses that cause cancers, like hepatitis B virus and human papillomavirus, these diseases can be prevented. Nonetheless, some cancer cells can avoid the immune system due to their rapid mutation and division. The immune response to many cancers involves three phases: elimination, equilibrium, and escape.
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