ナノスケールでのウイルスの相互作用とメカニズムをエクスパンション顕微鏡で可視化する

Expansion microscopy is a groundbreaking technique that enables nanoscale imaging of biological specimens using standard optical microscopes. By embedding specimens in swellable hydrogels, it achieves sub-diffraction resolution. Compatible with various tissue types, it offers 3D, multi-colour visualisation of cellular and sub-cellular structures. While challenges remain, like sample isotropy and preservation of molecular integrity, expansion microscopy is a transformative tool for cell and neurobiology. Here, we discuss its potential for virology.