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Updated: Jan 13, 2026

Author Spotlight: A Computational Approach to Decipher Amino Acid Preferences in Multispecific Protein-Protein Interactions
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Author Spotlight: A Computational Approach to Decipher Amino Acid Preferences in Multispecific Protein-Protein Interactions

Published on: January 26, 2024

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アミノ酸残留駆動ナノ粒子のタンパク質空洞の標的化:表面化学は,サイズ補完を超えた結合特異性を規定する

Fangfang Liu1,2, Guofang Zhang1,2, Xiaofeng Wang1,2

  • 1Laboratory of Inflammation and Vaccines, Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, 518055 Shenzhen, China.

Journal of the American Chemical Society
|January 7, 2026
PubMed
まとめ

ナノ粒子 (NP) は,以前は薬が効かないと考えられていたタンパク質の穴をターゲットにすることができます. 酸化セリウムNP (CeO2NPs) と黄金NP (AuNPs) は,SARS-CoV-2のスパイクトリマーに異なった結合をしており,選択的なNP結合の残留レベル認識を明らかにしている.

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