関連する実験動画

Updated: Jul 15, 2026

A Preclinical Mouse Model of Osteosarcoma to Define the Extracellular Vesicle-mediated Communication Between Tumor and Mesenchymal Stem Cells
11:15

A Preclinical Mouse Model of Osteosarcoma to Define the Extracellular Vesicle-mediated Communication Between Tumor and Mesenchymal Stem Cells

Published on: May 6, 2018

骨肉腫と間葉系幹細胞の相互作用を3D骨模倣共培養モデルで解読する

Giada Bassi1, Mohamed Saqawa2, Lorenzo Apolloni3

  • 1Institute of Science, Technology and Sustainability for Ceramics (ISSMC), National Research Council (CNR), Faenza 48018, Italy.

Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie
|January 7, 2026
PubMed
まとめ

骨肉腫の進行には、腫瘍微小環境（TME）内の間葉系幹細胞（MSC）が関与しています。新しい3D骨模倣モデルは、OS細胞、MSC、およびECM間の相互作用を明らかにし、TMEの研究を支援します。

キーワード:
3D共培養骨模倣スキャフォールド細胞外マトリックス間葉系幹細胞骨肉腫腫瘍微小環境

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関連する概念動画

Mesenchymal Stem Cells01:19

Mesenchymal Stem Cells

Mesenchymal stem cells (MSCs) are adult stem cells that can differentiate into most connective tissue cell types, except for hematopoietic cells, depending upon the source of MSCs. For example, bone-marrow-derived MSCs (BM-MSCs) can differentiate into osteocytes, hepatocytes, and pancreatic and neuronal cells. MSCs can be isolated from various sources such as bone marrow, placenta, adipose tissue, teeth, and Wharton’s jelly, a gelatinous substance in the umbilical cord. The ease of their access...