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Drug Dosing: Geriatric Patients01:15

Drug Dosing: Geriatric Patients

219
Elderly individuals encompass a diverse population with varying degrees of age-related physiological changes. Defining the elderly presents challenges, as the geriatric population is often arbitrarily categorized as individuals older than 65. However, many individuals in this group lead active and healthy lives, with an increasing number surpassing 85 years and falling into the older elderly category. Physiological changes associated with aging impact performance capacity and homeostatic...
219
Pharmacodynamics in Geriatric Patients: Effects of Age01:27

Pharmacodynamics in Geriatric Patients: Effects of Age

183
Age-related pharmacokinetic changes are extensively documented, but understanding age-related pharmacodynamic alterations is relatively limited. This knowledge gap can be partly attributed to the complexity of developing appropriate measures of drug responses compared to bioanalytical methods for determining drug concentrations.Most information regarding age-related differences in human pharmacodynamics originates from cross-sectional studies. However, these studies assume that observed mean...
183
Methods of Documentation VI: Case Management Model01:15

Methods of Documentation VI: Case Management Model

852
The case management model is a multidisciplinary approach that involves healthcare professionals from diverse disciplines, such as physicians, nurses, therapists, social workers, and pharmacists, working collaboratively to address the various needs of patients. Each healthcare professional brings unique expertise and perspectives, contributing to a more comprehensive understanding of the patient's condition and tailoring treatment plans accordingly.
For example, a patient with a chronic...
852
Peripheral Artery Disease III: Interprofessional Care01:27

Peripheral Artery Disease III: Interprofessional Care

236
Peripheral Artery Disease (PAD) is characterized by narrowed arteries that diminish blood flow to the extremities. Effective management of PAD requires an interprofessional approach involving various healthcare professionals. The critical aspects of interprofessional care for PAD patients focus on risk factor modification, drug therapy, exercise therapy, nutrition therapy, critical limb ischemia care, and interventional radiology and surgical procedures.The primary treatment goal for PAD...
236
Pharmacokinetics in Geriatric Patients: Effect of Age on Drug Absorption01:22

Pharmacokinetics in Geriatric Patients: Effect of Age on Drug Absorption

223
As individuals age, their body's physiology evolves, affecting drug pharmacokinetics. The most apparent changes occur in the gastrointestinal tract, where an increase in gastric pH, a delay in gastric emptying, and a reduction in gastrointestinal motility are observed. Remarkably, these changes do not substantially modify the absorption of orally administered drugs, particularly those absorbed via passive diffusion.Transdermal drug delivery emerges as a highly viable method for older adults due...
223
Pharmacokinetics in Geriatric Patients: Effect of Age on Drug Metabolism01:18

Pharmacokinetics in Geriatric Patients: Effect of Age on Drug Metabolism

194
Geriatric patients show significant variation in how their bodies process medications, which can change how effective and safe treatments are. The liver is the primary organ where drug metabolism occurs, involving two main types of chemical reactions: phase I and II. Phase I metabolism is driven by the cytochrome P450 enzyme system, which includes key types such as CYP3A, CYP2D6, and CYP2C9. Research indicates that while aging doesn't notably alter the levels or activity of these enzymes, it...
194

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関連する実験動画

Updated: Jan 13, 2026

E-Patient Counseling Trial E-PACO: Computer Based Education versus Nurse Counseling for Patients to Prepare for Colonoscopy
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高齢者向け老年外科共同管理プログラムの開発と実施：文書分析からの洞察

Abigail Baim-Lance1,2, Fred Ko1,2, William Hung1,2

  • 1Icahn School of Medicine at Mount Sinai, New York (NY).

Surgery in geriatrics and frailty
|January 7, 2026
PubMed
まとめ

Aging, Life Innovations, Goals and Needs-Collaboration Achieving Readiness and Empowerment (ALIGN-CARE) プログラムは、虚弱な高齢者の手術準備を強化します。この学際的な共同管理モデルは、適応戦略とステークホルダーの協力によって進化しました。

キーワード:
文書分析老年外科共同管理実施戦略プログラム開発

さらに関連する動画

A Training Program Using an Agility Ladder for Community-Dwelling Older Adults
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A Training Program Using an Agility Ladder for Community-Dwelling Older Adults

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Last Updated: Jan 13, 2026

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科学分野:

  • 老年医学
  • 外科的ケア
  • ヘルスケアプログラム開発

背景:

  • 虚弱な高齢者は、手術のための特別な準備を必要とします。
  • 学際的な共同管理モデルは、この集団の手術成績を改善することができます。

研究 の 目的:

  • ALIGN-CARE外来老年外科共同管理プログラムの開発と実施を調査すること。
  • 高齢者向け複雑な学際的プログラムの進歩を支援する主要なプロセスと戦略を特定すること。

主な方法:

  • Medical Research Council (MRC) 評価フレームワークを利用しました。
  • 84回のプログラム会議（2020年1月～2022年1月）の文書レビューとテーマ分析を実施しました。
  • 諮問、学際的、外科医、研究の4つの定期的な会議タイプを分析しました。

主要な成果:

  • ALIGN-CAREプログラムは、紹介、スケジューリング、評価、計画という4つのコアコンポーネントを進化させ、安定させました。
  • プログラムの柔軟性と応答性が、実施における重要な推進力となりました。
  • ステークホルダー会議は、プログラムの適応と成熟を促進しました。

結論:

  • 文書分析方法は、老年外科共同管理の開発に不可欠なプロセスを特定しました。
  • ALIGN-CAREの開発は、複雑な学際的プログラムにおける適応戦略の重要性を強調しています。
  • この研究は、手術を受ける高齢者のケアを進歩させるための洞察を提供します。