骨折管理デバイス用積層造形17-4 PHステンレス鋼

Stainless steel 316L (SS316L) is widely used in fracture management devices. However, SS316L does not offer any bacterial infection resistance and can cause metal-ion sensitivity due to Ni-ions' presence. 17-4PH can emerge as a promising substitute due to the intrinsic antibacterial properties of copper, a 75% reduction in nickel content, and superior mechanical properties. SS316L and 17-4 PH were manufactured using laser-directed energy deposition (LDED). 17-4PH specimens surpassed the compressive strength of SS316L by over 150%. A static magnetic field was generated in 17-4 PH specimens to understand in vitro bone cell-material interactions. In vitro human fetal osteoblast cell culture and bacterial inhibition study using Staphylococcus aureus and Pseudomonas aeruginosa were carried out on these specimens with SS316L as control and as-processed and magnetized 17-4 PH as treatments. Results demonstrated that magnetized 17-4 PH exhibited 25% enhancement in hFOB proliferation and 70% reduction in bacterial colonization compared to SS316L.