関連する実験動画

Updated: Jan 13, 2026

Three-dimensional Confocal Analysis of Microglia/macrophage Markers of Polarization in Experimental Brain Injury
13:28

Three-dimensional Confocal Analysis of Microglia/macrophage Markers of Polarization in Experimental Brain Injury

Published on: September 4, 2013

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UNC5BはDAPK3/MVK経路を介して脳卒中後のミクログリアのパイロプトーシスを促進する

Ying Luo1,2, Songjie Liao1, Meiling Yao1

  • 1Department of Neurology, The First Affiliated Hospital, Sun Yat-Sen University; Guangdong Provincial Key Laboratory of Diagnosis and Treatment of Major Neurological Diseases; National Key Clinical Department and Key Discipline of Neurology, No. 58 Zhongshan Road 2, 510080, Guangzhou, China.

Neurochemical research
|January 7, 2026
PubMed
まとめ

Uncoordinated-5 homolog B (UNC5B)は、DAPK3-MVK経路を介したパイロプトーシスの活性化により、脳卒中後の脳細胞死を促進する。UNC5Bまたはこの経路の阻害はニューロンを保護し、脳卒中回復のための潜在的な治療標的を提供する。

キーワード:
DAPK3MVKパイロプトーシス脳卒中UNC5B

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