MERS様コロナウイルスのヒトDPP4受容体認識の構造基盤 2014-422およびGX2012
Zichun Lin1,2,3, Teng Gao1,2, Xinquan Wang1,2,3
1Beijing Frontier Research Center for Biological Structure, Beijing, China.
PLoS pathogens
|January 7, 2026
まとめ
コウモリ由来の2つの新規MERS様コロナウイルスはヒトDPP4に結合します。構造解析により、余分な残基が原因で結合角度が変化し、受容体認識に影響を与え、Merbecovirusのサーベイランスに洞察を提供することが明らかになりました。
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