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Updated: Jan 13, 2026

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TimeFlow 2: Flow Cytometryデータのための教師なし細胞系統検出手法

Margarita Liarou1, Thomas Matthes2,3, Stéphane Marchand-Maillet1

  • 1Department of Computer Science, University of Geneva, Carouge, Switzerland.

Cytometry. Part A : the journal of the International Society for Analytical Cytology
|January 8, 2026
PubMed
まとめ

TimeFlow 2は、事前の知識なしに静的なフローサイトメトリーデータから細胞分化経路を推定します。この手法は、細胞系統とマーカーダイナミクスを正確にモデル化し、既存のツールを上回る性能を発揮します。

キーワード:
骨髄データ細胞分化フローサイトメトリー最適輸送パスクラスタリング擬似時間解析軌跡推論

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Flow Cytometry01:23

Flow Cytometry

The development of flow cytometry techniques began in 1934 with initial attempts by Andrew Moldavan, a bacteriologist who counted the cells in a flowing capillary system. Moldavan pumped cells through a capillary tube focused under a microscope for visualization. The invention of photometry allowed the measurement of differentially-stained cells, and Louis Kamentsky developed the first multiparameter flow cytometer in 1965 to identify and count the cancer cells in cervical tissue specimens.
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