関連する実験動画

Updated: Jun 25, 2026

Atomic Force Microscopy Investigations of DNA Lesion Recognition in Nucleotide Excision Repair
10:59

Atomic Force Microscopy Investigations of DNA Lesion Recognition in Nucleotide Excision Repair

Published on: May 24, 2017

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DNA塩基性部位反応性ダイナミクスの単一分子アンカー支援ナノポアプロファイリング

Zhuoqun Su1, Wanxiao Wang1, Liuxin Jiao1

  • 1School of Food Science and Engineering, Shaanxi University of Science and Technology, Xi'an, Shaanxi 710021, China.

Analytical chemistry
|January 9, 2026
PubMed
まとめ

研究者らは、塩基性部位（AP）部位のような反応性DNA中間体をリアルタイムで追跡するための新しいナノポア法を開発しました。この技術は、ビタミンB12アンカーを使用してDNAを固定化し、DNA修復ダイナミクスと反応の詳細な研究を可能にします。

キーワード:
ナノポア塩基性部位DNA修復単一分子ビタミンB12化学反応バイオセンサー生化学ナノテクノロジー

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関連する概念動画

Nucleic Acid Structure01:25

Nucleic Acid Structure

The pentose sugar in DNA is deoxyribose, while in RNA the pentose sugar is ribose. The difference between the sugars is the presence of the hydroxyl group on the ribose's second carbon and a hydrogen on the deoxyribose's second carbon. The phosphate residue attaches to the hydroxyl group of the 5′ carbon of one sugar and the hydroxyl group of the 3′ carbon of the sugar of the next nucleotide, which forms  a 5′ to 3′ phosphodiester linkage.
DNA Structure
DNA has a double-helix structure. The...