計画Aがうまくいかない場合：免疫寛容の標的としてのCD47細胞外ドメイン
Enrique Montero1,2, Jeffrey S Isenberg3,2
1Department of Diabetes Immunology, 1500 Duarte Road, Duarte, CA 91010, USA.
Cells
|January 9, 2026
まとめ
がん治療のためのCD47細胞外ドメイン（ECD）の標的化は、PD-L1 ECDブロッカーとは異なり、限定的な成功しか示していません。将来の戦略では、自己免疫疾患の寛容を調節するためにCD47 ECDを探求する可能性があります。
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