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Updated: May 8, 2026

Monitoring the Effects of Illumination on the Structure of Conjugated Polymer Gels Using Neutron Scattering
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欧州核破砕源における中性子タンパク質結晶構造解析の見通し

Esko Oksanen1

  • 1Division of Computational Chemistry, Lund University, Lund, Sweden; European Spallation Source ESS ERIC, Lund, Sweden; LINXS - Institute of Advanced Neutron and X-ray Science, Lund, Sweden.

Structure (London, England : 1993)
|January 9, 2026
PubMed
まとめ

欧州核破砕源は、高度な中性子タンパク質結晶構造解析能力を提供する。分子レベルの生物学的研究でこの高い中性子流を利用するには、専用の施設が不可欠である。

キーワード:
中性子タンパク質結晶構造解析欧州核破砕源構造生物学高分解能構造解析分子生物学

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Conventional electron microscopy (EM) involves dehydration, fixation, and staining of biological samples, which distorts the native state of biological molecules and results in several artifacts. Also, the high-energy electron beam damages the sample and makes it difficult to obtain high-resolution images. These issues can be addressed using cryo-EM, which uses frozen samples and gentler electron beams. The technique was developed by Jacques Dubochet, Joachim Frank, and Richard Henderson, for...