肥満と新型コロナウイルス感染後症状(Post-COVID-19 Condition)との関連性:兵役義務者コホート研究
Reinhard Domanyi1,2, Emanuel Maitz2, Alexandros Andrianakis2
1Military Hospital Graz, 8052 Graz, Austria.
Journal of clinical medicine
|January 10, 2026
まとめ
ボディマス指数(BMI)および腹囲/身長比(WHtR)で測定される肥満は、新型コロナウイルス感染後症状を発症するリスクの増加と関連している。これは、WHtRが長期的なCOVID症状を発症しやすい個人を特定するのに役立つ可能性を示唆している。
科学分野:
- 公衆衛生
- 疫学
- 身体計測学
背景:
- 肥満は新型コロナウイルス感染後症状の潜在的なリスク因子である。
- BMIのような従来の指標は、体脂肪分布を完全には捉えきれない。
- 腹囲/身長比(WHtR)は、中心性肥満および体脂肪分布の指標である。
研究 の 目的:
- BMIおよびWHtRによって定義される肥満と新型コロナウイルス感染後症状との関連を調査すること。
- WHtRが長期的なCOVID症状に関連する体脂肪分布の代理指標として機能するかどうかを評価すること。
主な方法:
- 18歳男性兵役義務者500名のコホートを評価した。
- 身長、体重、腹囲を含む身体計測値の測定を行った。
- 参加者はCOVID-19罹患後の持続的または新規の症状を報告した。BMIおよびWHtR(中心性肥満の場合は≧0.50)を算出した。
主要な成果:
- 既往のCOVID-19罹患経験のある参加者376名のうち、21%が新型コロナウイルス感染後症状を経験した。
- BMI定義による肥満(≧30)は、新型コロナウイルス感染後症状を有する者でより一般的であり(15% vs 5%)、オッズ比(OR)2.80で関連していた。
- 中心性肥満(WHtR ≧0.50)もより頻繁に見られ(26% vs 14%)、オッズ比(OR)2.18の増加と関連していた。
結論:
- BMI定義による肥満および中心性肥満の両方が、新型コロナウイルス感染後症状と関連している。
- WHtRは、長期的なCOVID症状のリスクが高い個人を特定するのに役立つ可能性のある、シンプルで実行可能な指標である。
- 長期的なCOVID症状のリスク層別化のための身体計測指標に関するさらなる研究が保証される。
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