関連する実験動画

Updated: May 13, 2026

Live Imaging and Quantification of Viral Infection in K18 hACE2 Transgenic Mice Using Reporter-Expressing Recombinant SARS-CoV-2
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定量的組織プロテオミクスは、ハムスターにおけるSARS-CoV-2変異株感染に関連するタンパク質シグネチャを明らかにする

Justin J Frere1,2,3, Boris Bonaventure1,4, Haylen T Rosberger1

  • 1Department of Microbiology, Icahn School of Medicine at Mount Sinai, New York, New York 10029, United States.

Journal of proteome research
|January 10, 2026
PubMed
まとめ

SARS-CoV-2変異株に対する宿主応答は異なる。ハムスターにおけるデルタ変異株感染は、気管線毛の消失と肺線維症に関連して、より大きな体重減少を引き起こし、すべての変異株で細胞増殖を抑制した。

キーワード:
COVID-19SARS-CoV-2ハムスター病原性ホスホプロテオミクスプロテオミクス

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関連する概念動画

Proteomics01:33

Proteomics

A proteome is the entire set of proteins that a cell type produces. We can study proteomes using the knowledge of genomes because genes code for mRNAs, and the mRNAs encode proteins. Although mRNA analysis is a step in the right direction, not all mRNAs are translated into proteins.
Proteomics is the study of proteomes' function. It involves the large-scale systematic study of the proteome to denote the protein complement expressed by a genome. Scientist Mark Wilkins coined the term proteomics...