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Updated: Jan 13, 2026

Comprehensive Evaluation of the Effectiveness and Safety of Placenta-Targeted Drug Delivery Using Three Complementary Methods

Comprehensive Evaluation of the Effectiveness and Safety of Placenta-Targeted Drug Delivery Using Three Complementary Methods

Published on: September 10, 2018

多発性硬化症における妊娠および乳児の転帰：グローバルMAPLE-MS医薬品安全性監視プログラムからの知見の概要

Kerstin Hellwig¹, Hugh H Tilson², Sandra Thiel³

¹Neurological Clinic, University of Bochum, Bochum, Germany.

Neurology and therapy

|January 10, 2026

Abstract:

Information on pregnancy and infant outcomes after cladribine tablets exposure is limited, as its use is not recommended during pregnancy. This is a summary of the original published article 'Pregnancy and infant outcomes in multiple sclerosis: findings from the Global MAPLE-MS Pharmacovigilance Program'. The primary outcome is the prevalence of major congenital anomalies (MCAs) in babies. Secondary outcomes include other pregnancy outcomes (live birth, elective termination, spontaneous abortion, ectopic pregnancy, and stillbirth).

キーワード:

多発性硬化症クラドリビン錠剤妊娠乳児の転帰医薬品安全性監視

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