海洋由来内生菌Eutypella sp. XLE005から単離された2つの新規化合物

¹College of Life Science, Key Laboratory of Microbial Diversity Research and Application of Hebei Province, Hebei University, Baoding, China.

|January 10, 2026

Abstract:

Two previously undescribed compounds, designated ochratoxin A iso-butyric acid ester (1) and iso-crytoporic acid I (2), were isolated from the rice fermentation broth of an endophytic fungus Eutypella sp. XLE005, which was obtained from the marine mollusk Conus leopardus (Röding). Structural characterisation was accomplished through extensive HR-ESI-MS and NMR spectroscopic analyses. Both compounds were screened for antibacterial and antifungal properties. Compound 2 exhibited weak antibacterial effects against Vibrio owensii, Streptococcus agalactiae, Aeromonas hydrophila, Aeromonas vickerii, and Vibrio rotiferianus, with inhibition rates of 56.29 ± 2.25%, 44.93 ± 5.97%, 58.12 ± 8.47%, 44.70 ± 1.01%, and 47.84 ± 7.40%, respectively, at 128 μg/mL.

キーワード:

Conus leopardus (Röding)Eutypella sp.抗菌活性内生菌

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