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Updated: Jan 13, 2026

Mechanical Stimulation-induced Calcium Wave Propagation in Cell Monolayers: The Example of Bovine Corneal Endothelial Cells
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パ ン ネ キ シ ン 研 究 25 年 の 回 顧

Daan Peeters1, Mathieu Vinken1, Raf Van Campenhout1

  • 1Entity of In Vitro Toxicology and Dermato-Cosmetology, Department of Pharmaceutical and Pharmacological Sciences, Vrije Universiteit Brussel, Brussels 1090, Belgium.

Current opinion in immunology
|January 10, 2026
PubMed
まとめ

パ ン ネ キ シ ン チ ャ ン ネ ル は 細胞 シ グ ナ ル 伝 達 、 炎 症 、 細 胞 死 を 調 節 す る 。 こ の レ ビ ュ ー で は 、 パ ン ネ キ シ ン 機 能 と 様 々 な 疾 患 に お け る そ の 役 割 に つ い て 25 年 間 の 研 究 を ま と め 、 そ の 治 療 的Potentiel を 強 調 す る 。

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Gap Junctions01:27

Gap Junctions

The cytoplasm of adjacent animal cells can exchange small molecules, ions, and secondary messengers via the communication channels which form the gap junctions. These junctions comprise a few hundred to thousands of molecular channels, each made of two halves, called the connexon hemichannel. A connexon is a hexamer of six transmembrane connexin proteins, which assemble radially, thus forming a pore or channel in the center. One connexon hemichannel docks with a corresponding connexon on the...
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