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概日リズムと不安の関係における性差:全国規模の人口調査
Jungyon Yum1, Soomi Cho2, Woo-Seok Ha2
1Department of Neurology, Yongin Severance Hospital, Yonsei University College of Medicine, Yongin, Republic of Korea.
Journal of psychiatric research
|January 10, 2026
まとめ
朝型の概日リズムは男性の不安リスクを低下させる可能性があるが、女性ではそうではない。これは、睡眠パターンと不安の関係における性差の可能性を浮き彫りにし、個別化された予防戦略が必要であることを示唆している。
科学分野:
- 睡眠科学
- 精神医学
- 生物時計学
背景:
- 不安と概日リズムの関連における性差の調査。
- 睡眠覚醒サイクルとメンタルヘルスの関係の理解。
研究 の 目的:
- 概日リズムと不安の関連における性差の可能性を検討する。
- 概日リズムが男性と女性で不安リスクに異なる影響を与えるかどうかを特定する。
主な方法:
- 2838人の成人(20〜59歳)の全国規模の人口ベースデータ分析。
- 概日リズムは朝型・夜型質問票を使用して評価。
- 不安レベルは一般化不安障害-7尺度で測定し、共変量を調整。
主要な成果:
- 女性(12.2%)の方が男性(7.4%)よりも不安の有病率が高く、夜型群(15.3%)で最も高かった。
- 朝型の男性は、中間型の概日リズムを持つ男性と比較して、有意に不安のリスクが低かった。夜型男性では有意な関連は見られなかった。
- 女性では、概日リズムと不安の間に関連は見られなかった。
結論:
- 概日リズムと不安の関連には有意な性差が存在する。
- 朝型の概日リズムは男性の不安に対する保護効果をもたらす可能性があるが、女性では観察されなかった。
- 性別に特化した、概日リズムを標的とした介入は、不安の予防と管理に有益である可能性がある。
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