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関連する概念動画

Anatomy of the Genitourinary System II: Bladder and Urethra01:19

Anatomy of the Genitourinary System II: Bladder and Urethra

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The lower urinary system consists of the urinary bladder and urethra, which are essential in storing and expelling urine from the body. Together with the internal and external sphincters, these structures work together to regulate urination effectively.Anatomy of the BladderThe urinary bladder is a muscular, stretchable organ behind the pubic bone and in front of the rectum. In females, the bladder is positioned anterior to the vagina and inferior to the uterus, while in males, it is located...
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Urinary Bladder01:23

Urinary Bladder

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The urinary bladder is a hollow, muscular sac that temporarily stores urine before it is expelled from the body. It can hold approximately 600 mL of urine prior to micturition. The bladder is retroperitoneal and located behind the pubic symphysis in the pelvic floor.
In males, the bladder is situated in front of the rectum, while in females, it is positioned anterior to the vagina and uterus. The bladder floor contains an inverted triangular area called the trigone, defined by the two ureteric...
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Urodynamic Studies: Uroflowmetry01:19

Urodynamic Studies: Uroflowmetry

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Uroflowmetry is a non-invasive urodynamic test designed to measure various aspects of urination, including volume, flow rate, and the time to void. This test is crucial for diagnosing and assessing conditions such as bladder outlet obstruction, bladder dysfunction, incomplete bladder emptying, incontinence, and urinary tract blockages caused by benign prostatic hyperplasia (BPH) and urethral strictures.Pre-Test Instructions:Before a uroflowmetry test, patients are typically advised to drink...
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Satellite Stem Cells and Muscular Dystrophy01:21

Satellite Stem Cells and Muscular Dystrophy

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Satellite stem cells or myosatellite cells are quiescent stem cells that Alexander Mauro first identified in 1961. These cells are located between the sarcolemma, the plasma membrane of muscle fibers, and the basal lamina, the connective tissue sheath covering it. These mononucleated cells are activated in response to muscle injury, can transform into myoblasts, and may form or repair muscle fibers. Myosatellite cells can provide additional myonuclei for muscle regeneration or return to a...
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Disorders of the Urinary System01:20

Disorders of the Urinary System

1.1K
The urinary system is responsible for eliminating waste and excess fluids from the body. However, disorders of the urinary system can arise due to various reasons like infections, stress, age, congenital abnormalities, and lifestyle.
Urinary tract infections (UTIs) are one of the most common urinary system disorders. They are caused by bacteria that enter the urethra and can spread to the bladder resulting in cystitis. Pyelonephritis is the result of a UTI that has ascended to the level of the...
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The Micturition Reflex01:26

The Micturition Reflex

2.4K
Urination, or micturition involves the coordination of the bladder's detrusor muscle and two sphincters to ensure controlled bladder emptying.
The process begins with bladder filling, where the bladder wall stretches as urine accumulates. This stretching activates the urine storage reflex, mediated by the sacral spinal segments and the pontine storage center. Efferent sympathetic impulses stimulate the detrusor muscle to relax and the internal urethral sphincter to contract, facilitating...
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Updated: Jan 13, 2026

Evaluation of Biomaterials for Bladder Augmentation using Cystometric Analyses in Various Rodent Models
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デュシェンヌ型筋ジストロフィーにおける膀胱機能障害：ナラティブレビュー

R R Kikkert1, J M Fock2, G J F J Bos3

  • 1Department of Urology, University Medical Centre Groningen, the Netherlands.

Journal of pediatric urology
|January 11, 2026
PubMed
まとめ

デュシェンヌ型筋ジストロフィー（DMD）は、しばしば尿路および腸の問題を引き起こします。このレビューは、下部尿路症状（LUTS）と排便障害の高い発生率を強調し、集学的治療を求めています。

キーワード:
膀胱機能障害デュシェンヌ型筋ジストロフィー下部尿路症状尿力学的検査

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Measurements of Motor Function and Other Clinical Outcome Parameters in Ambulant Children with Duchenne Muscular Dystrophy
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Measurements of Motor Function and Other Clinical Outcome Parameters in Ambulant Children with Duchenne Muscular Dystrophy

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Detrusor Underactivity Model in Rats by Conus Medullaris Transection
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Detrusor Underactivity Model in Rats by Conus Medullaris Transection

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Evaluation of Biomaterials for Bladder Augmentation using Cystometric Analyses in Various Rodent Models
10:19

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Measurements of Motor Function and Other Clinical Outcome Parameters in Ambulant Children with Duchenne Muscular Dystrophy
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Detrusor Underactivity Model in Rats by Conus Medullaris Transection
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科学分野:

  • 泌尿器科学
  • 神経学
  • 小児科学

背景:

  • デュシェンヌ型筋ジストロフィー（DMD）は、重度の進行性骨格筋疾患です。
  • DMDにおける泌尿器合併症には、尿失禁、膀胱低活動、尿失禁、排尿筋括約筋協調不全、および尿路結石症が含まれます。
  • このレビューは、DMD患者における膀胱機能障害の管理に焦点を当てています。

研究 の 目的:

  • DMD児における下部尿路症状（LUTS）、排便障害、尿路感染症（UTI）、および尿路結石症の発生率を調査すること。
  • DMD児における泌尿器系問題が生活の質に及ぼす影響を評価すること。
  • DMDにおける膀胱機能障害の管理に関する推奨事項を提供すること。

主な方法:

  • PubMed、Scopus、Embase、Cochrane、およびWeb of Scienceを横断する包括的な文献検索を実施しました。
  • PRISMAガイドラインに従って9つの非ランダム化研究が選択され、PICOフレームワークを使用して分析されました。
  • 研究の質はMINORS基準を使用して検証されました。

主要な成果:

  • DMD患者におけるLUTSの有病率は32%から85%の範囲であり、躊躇、切迫感、失禁、頻尿が最も一般的でした。
  • 随伴する排便障害は、患者の32%から70%で報告されました。
  • 尿路感染症、尿路結石症、生活の質、および治療結果に関する情報は乏しかったです。

結論:

  • DMDは、特にLUTSおよび排便障害の高い有病率と関連しています。
  • DMDにおけるUTI、尿路結石症、生活の質、および治療効果に関するデータの著しい不足があります。
  • DMDにおけるLUTSおよび腸機能障害に対処するために、小児泌尿器科医を含む集学的管理が推奨されます。