網膜画像解析における曲率ベース、幅優先探索、ユークリッド距離を組み合わせた蛇行測定法の改良
Nur Asyiqin Amir Hamzah1,2, Wan Mimi Diyana Wan Zaki2, Aziah Ali3
1Centre of Advanced Analytics, Faculty of Engineering and Technology, Multimedia University, Jalan Ayer Keroh Lama, Melaka, Malaysia.
PeerJ
|January 12, 2026
まとめ
網膜血管の蛇行は、健康な眼では動脈と静脈で異なり、静脈の方が蛇行が大きい。撮影視野は測定値に大きく影響するため、診断精度には標準化が必要である。
科学分野:
- 眼科学および医用画像処理
- 生体医工学
- 定量的画像解析
背景:
- 網膜血管の蛇行は、全身疾患および眼疾患の重要なバイオマーカーである。
- 特に動脈と静脈の区別を含む定量的評価は、十分に調査されていない。
- 信頼性の高い蛇行分析には、標準化された方法が必要である。
主な方法:
- 分析のために3つの公開データセット(DRIVE、HRF、LES-AV)を使用した。
- 血管分節、動脈静脈分離、骨格化、視神経乳頭ベースの追跡を含むパイプラインを適用した。
- 堅牢な血管経路追跡と曲率ベースの指標のために幅優先探索(BFS)を使用した。
結論:
- 網膜血管の蛇行は、血管特異的で堅牢なバイオマーカーである。
- 測定値は、撮像パラメータ、特に視野と視神経乳頭の向きの影響を受ける。
- 診断アプリケーションおよびクロススタディ比較のためには、撮像パラメータの標準化が不可欠である。
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