関連する実験動画
Updated: Jan 13, 2026

10:42
Oral Biofilm Sampling for Microbiome Analysis in Healthy Children
Published on: December 31, 2017
17.8K
口腔矯正治療中の10代における唾液パラメータがう蝕発生に及ぼす影響
Vijender Kumar1, Ashim Roy2, Apna Yadav3
1Department of Orthodontics, MM College of Dental Sciences and Research, Ambala, Haryana, India.
Journal of pharmacy & bioallied sciences
|January 12, 2026
まとめ
口腔矯正治療は当初唾液分泌を促進するが、後にう蝕に対する防御力を低下させる。固定装置を装着している青年期においては、この高リスク期間中の早期予防ケアが極めて重要である。
科学分野:
- 口腔衛生研究、歯科う蝕予防、唾液診断
背景:
- 固定式口腔矯正装置は口腔環境を変化させる可能性があります。唾液パラメータは口腔衛生と齲蝕リスクの重要な指標です。口腔矯正治療を受けている青年は、歯科う蝕の脆弱な集団を代表します。
研究 の 目的:
- 青年期のう蝕病変(ACL)と唾液パラメータの関連性を調査すること。唾液パラメータ(CA VI、pH、緩衝能、アミラーゼ、SFR)の口腔矯正治療中の変化を評価すること。固定装置療法中のう蝕リスクの重要な時点を特定すること。
主な方法:
- 固定式口腔矯正装置を装着した100人の青年(12〜17歳)を対象とした縦断的観察研究。装置装着後、ベースラインおよび1、3、6、12ヶ月時点での刺激唾液サンプルを採取。唾液パラメータ(CA VI、pH、緩衝能、アミラーゼ、刺激唾液流量(SFR))を測定。Nyvadの基準によるACL診断。
主要な成果:
- 非ACL患者では、唾液流量(SFR)が1ヶ月で増加しました。緩衝能とα-アミラーゼレベルは、それぞれ3ヶ月と6ヶ月で有意に低下しました。炭酸脱水酵素VI(CA VI)は、SFRおよびpHと複雑な相関を示しました。新たなう蝕病変の発生は、約3ヶ月後の唾液防御力の低下と一致しました。
結論:
- 口腔矯正治療は早期の唾液流量変化を引き起こしますが、保護的な唾液因子の低下につながります。口腔矯正装置装着後3〜6ヶ月の間にう蝕の高リスク期が発生します。唾液パラメータが最終的に回復するにもかかわらず、この期間中の青年には早期の予防介入が推奨されます。
関連する概念動画
Teeth
1.6K
The formation of teeth, also known as odontogenesis, is a complex process that begins in utero, around the sixth week of embryonic development. There are three stages to this process: the bud stage, the cap stage, and the bell stage.
In the bud stage, the tooth germ (an aggregation of cells) starts to form in the developing jawbone. During the cap stage, the tooth germ differentiates into enamel organ, dental papilla, and dental sac, which will later develop into the tooth's enamel, dentin...
In the bud stage, the tooth germ (an aggregation of cells) starts to form in the developing jawbone. During the cap stage, the tooth germ differentiates into enamel organ, dental papilla, and dental sac, which will later develop into the tooth's enamel, dentin...
1.6K
Assessment of the Mouth
1.1K
A thorough mouth assessment, including inspection and palpation of the lips, gums, tongue, tonsils, uvula, and pharynx, is crucial in detecting potential health issues. Diseases ranging from oral cancer to systemic conditions like diabetes could be identified early through careful oral examination. This article provides a detailed guide on conducting a comprehensive mouth assessment.
Mouth Inspection
The inspection begins with visually examining the mouth for symmetry, color, and size.
Mouth Inspection
The inspection begins with visually examining the mouth for symmetry, color, and size.
1.1K
Tooth Anatomy
2.0K
The human tooth enables us to eat a variety of foods, speak clearly, and even aid in shaping our faces. Teeth are composed of various elements that work together. Here's a detailed look at the anatomy of a human tooth.
The Crown, Neck, and Root
The visible part of the tooth is referred to as the crown. It's covered by enamel, the hardest substance in the human body. The crown is uniquely shaped for each type of tooth, allowing for different functions such as cutting, tearing, or...
The Crown, Neck, and Root
The visible part of the tooth is referred to as the crown. It's covered by enamel, the hardest substance in the human body. The crown is uniquely shaped for each type of tooth, allowing for different functions such as cutting, tearing, or...
2.0K

