糖尿病乳腺病(DMP)の典型および非典型的な画像所見と病理学的特徴のスペクトル
Sanchanaa Sree Balakrishnan1, Bhawna Dev1, Leena Dennis Joseph2
1Department of Radiology, Sri Ramachandra Institute of Higher Education and Research, Chennai, Tamil Nadu, India.
Abstract:
Diabetic mastopathy (DMP) is a rare fibroinflammatory condition of the breast seen in patients with diabetes mellitus (DM), which mimics malignancy on imaging. We present eight cases of biopsy-proven DMP with typical (1/8 cases) and atypical (7/8 cases) imaging appearances and describe their histopathological features including duct dilatation/distortion, tight periductal cuffing by inflammatory infiltrates, type of inflammatory infiltrate, stromal fibrosis, epithelial fibroblasts, and grade of lobulitis (mild, moderate, and severe). Our case series depicts the varied atypical imaging findings in DMP and the indispensable role of histopathology in diagnosis. The postbiopsy diagnosis of DM in one of our patients highlights the possible role of histopathology in the detection of patients who may be prone to develop diabetes later. Our series also showed a lack of correlation between the radiopathological findings and clinical features such as duration or type of DM, treatment, and glycemic control status.
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