院外心停止に対する体外式心肺蘇生における男女格差
Akira Kawauchi1,2, Yohei Okada3,4, Makoto Aoki5
1Department of Critical Care and Emergency Medicine, Japanese Red Cross Maebashi Hospital, Gunma, Japan.
Critical care medicine
|January 13, 2026
まとめ
院外心停止(OHCA)の男性患者は、ECPRを受ける可能性が有意に高かった。この男女格差は、ECPR適格性が不明確な場合に最も顕著であり、さらなる調査が必要である。
科学分野:
- 循環器病学;救急医学;公衆衛生
背景:
- 院内および院外での心停止治療には男女格差が存在する。;院外心停止(OHCA)に対する体外式心肺蘇生(ECPR)における性差に関するエビデンスは限られている。
研究 の 目的:
- OHCA患者に対するECPR投与における潜在的な男女格差を調査すること。;OHCA症例におけるECPR利用に性別が影響するかどうかを特定すること。
主な方法:
- 前向き全国レジストリ(JAAM-OHCA)の二次分析。;病院到着前に自発呼吸の再開がない成人OHCA患者を含めた。;患者およびセンターの変数を調整してECPR投与を分析するための多変量ロジスティック回帰。
主要な成果:
- ECPRは男性患者の6.0%、女性患者の1.8%に投与された(n=47,965)。;調整後、男性はECPRを受けるオッズが有意に高かった(OR、1.68; 95% CI、1.46-1.93)。;ECPR使用における男性優位は、適格性または不適格性が明確な場合を除き、サブグループ全体で一貫していた。
結論:
- OHCAの男性患者は、女性患者よりも有意に頻繁にECPRを受けた。;ECPR投与における男女格差は、曖昧な症例でより顕著であるように思われる。;観察されたECPR利用におけるこの男女格差の背後にある理由を解明するためには、さらなる研究が必要である。
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