β作動薬の作用機序
Sara J Trojan1, Jerilyn Hergenreder2
1Peak Beef Nutrition Consulting, LLC, Casper, WY 82604, USA.
Abstract:
Beta-adrenergic agonists and selective β-adrenergic modulators are unique growth promoting technologies that elicit responses independent of growth implants. These compounds work through specific receptors located throughout the body to increase protein accretion through signaling events leading to metabolic modulation. The β-adrenergic recetors differ in their physiologic location and active life. Prolonged exposure of β1 and β2 receptors to ligands causes desensitization and receptor internalization, whereas β3 receptors differ in structure and have an extended half-life. Three β-adrenergic agonists and selective β-adrenergic modulators have been approved for use in cattle feeding in the United States.
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