Jove
Visualize
お問い合わせ
JoVE
x logofacebook logolinkedin logoyoutube logo
JoVEについて
概要リーダーシップブログJoVEヘルプセンター
著者向け
出版プロセス編集委員会範囲と方針査読よくある質問投稿
図書館員向け
推薦の声購読アクセスリソース図書館諮問委員会よくある質問
研究
JoVE JournalMethods CollectionsJoVE Encyclopedia of Experimentsアーカイブ
教育
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab Manual教員リソースセンター教員サイト
利用規約
プライバシーポリシー
ポリシー

関連する概念動画

Muscles of the Eye01:20

Muscles of the Eye

3.9K
The muscles of the eye are sophisticated structures that control eye movement and focus, allowing for the precise and rapid adjustments necessary for vision. The human eye is controlled by ten muscles — six extraocular muscles, three intraocular muscles, and one primary eyelid retractor muscle.
Extraocular Muscles
The six extraocular muscles surround the eyeball and control its movements. They are responsible for a wide range of eye motions, including looking up, down, left, right, and...
3.9K
Accessory Structures of the Eye01:17

Accessory Structures of the Eye

3.4K
Optical perception, or vision, is an extraordinary sense dependent on converting light signals received via the ocular organs. These organs, known as eyes, are securely positioned within the bony cavities of the skull, called orbits. The orbits serve a dual purpose: a protective shield for the ocular globes and a stable attachment point for the soft ocular tissues. The eye's external protective mechanisms include the eyelids, which are edged with lashes that act as a barrier against foreign...
3.4K
Open Angle Glaucoma: Treatment01:27

Open Angle Glaucoma: Treatment

963
In open-angle glaucoma, the iridocorneal angle remains open, but the trabecular meshwork becomes stiff, slowing down the outflow of aqueous humor. This causes a buildup of aqueous humor in the anterior chamber, leading to a sudden increase in intraocular pressure. The treatment for open-angle glaucoma focuses on reducing the elevated intraocular pressure by either decreasing the secretion of aqueous humor or increasing its outflow.
Drugs such as carbonic anhydrase inhibitors, α2- and...
963
Glaucoma: Overview01:25

Glaucoma: Overview

1.2K
Glaucoma is an eye condition characterized by increased intraocular pressure that damages the retina and optic nerve, leading to irreversible blindness if left untreated. The human eye has various components, including the cornea, iris, pupil, lens, and optic nerve. Aqueous humor is secreted by the epithelium of the ciliary body in the posterior chamber and flows through the trabecular meshwork and canal of Schlemm, maintaining normal intraocular pressure. The trabecular meshwork and the canal...
1.2K
Angle Closure Glaucoma: Treatment01:28

Angle Closure Glaucoma: Treatment

1.2K
Angle-closure glaucoma, or closed-angle glaucoma, is an eye condition where the iris bulges out and blocks the iridocorneal angle, resulting in a buildup of aqueous humor and increased intraocular pressure. Immediate medical attention is necessary due to the sudden onset of symptoms. The treatment for angle-closure glaucoma includes short-term and long-term approaches. Short-term treatment involves using eye drops like pilocarpine to lower intraocular pressure by increasing aqueous humor...
1.2K
Focusing of Light in the Eye01:16

Focusing of Light in the Eye

5.4K
Light rays enter the eye through the cornea, a transparent dome-shaped tissue that is the eye's outermost layer. The cornea bends or refracts, light rays traveling to the pupil. The shape of the cornea determines how much of the light is bent and whether the image will be focused correctly on the retina at the back of the eye. Once the light has passed through both refraction layers, it converges into a single focal point onto a small area. This is where photoreceptors start transforming...
5.4K

こちらも読む

関連記事

共著者、ジャーナル、引用グラフによってこの研究に関連する記事。

並び替え
Same author

Analysis of human visual experience data.

Journal of vision·2026
Same author

Repeatability of SpotChecks contrast sensitivity test in macular disease.

Optometry and vision science : official publication of the American Academy of Optometry·2026
Same author

Time of Day Effects of Contact Lens-Induced Full-Field and Peripheral-Field Defocus on Choroidal Thickness: A Pilot Study in Adults.

Eye & contact lens·2026
Same author

Retinal Safety of a Red Light Myopia Therapy Device-Reply.

JAMA ophthalmology·2026
Same author

Dose-Response Characteristics of Retinal Inactivation Due to Intravitreal Injections of Tetrodotoxin in Nonhuman Primates.

Investigative ophthalmology & visual science·2026
Same author

Gender and Refractive Error Stratified Ocular Biometry Percentile Curves in Indian School Children.

Ophthalmic & physiological optics : the journal of the British College of Ophthalmic Opticians (Optometrists)·2026

関連する実験動画

Updated: Jan 17, 2026

Inducement and Evaluation of a Murine Model of Experimental Myopia
07:20

Inducement and Evaluation of a Murine Model of Experimental Myopia

Published on: January 22, 2019

10.5K

実験的近視眼における眼球剛性

Suharsha Paidimarri1, Nimesh B Patel1, Krista M Beach1

  • 1University of Houston, College of Optometry, 4401 Martin Luther King Blvd, Houston, Texas 77204.

Experimental eye research
|January 14, 2026
PubMed
まとめ

アカゲザルにおける形態剥奪近視は、有意な眼球伸長と近視シフトを引き起こしたが、眼球剛性は変化しなかった。この研究は、近視発生における眼球生体力学への洞察を提供する。

キーワード:
生体力学近視眼球剛性強膜

さらに関連する動画

Full-Circle Cauterization of Limbal Vascular Plexus for Surgically Induced Glaucoma in Rodents
10:10

Full-Circle Cauterization of Limbal Vascular Plexus for Surgically Induced Glaucoma in Rodents

Published on: February 15, 2022

1.8K
A Model of Glaucoma Induced by Circumlimbal Suture in Rats and Mice
07:00

A Model of Glaucoma Induced by Circumlimbal Suture in Rats and Mice

Published on: October 5, 2018

10.9K

関連する実験動画

Last Updated: Jan 17, 2026

Inducement and Evaluation of a Murine Model of Experimental Myopia
07:20

Inducement and Evaluation of a Murine Model of Experimental Myopia

Published on: January 22, 2019

10.5K
Full-Circle Cauterization of Limbal Vascular Plexus for Surgically Induced Glaucoma in Rodents
10:10

Full-Circle Cauterization of Limbal Vascular Plexus for Surgically Induced Glaucoma in Rodents

Published on: February 15, 2022

1.8K
A Model of Glaucoma Induced by Circumlimbal Suture in Rats and Mice
07:00

A Model of Glaucoma Induced by Circumlimbal Suture in Rats and Mice

Published on: October 5, 2018

10.9K

科学分野:

  • 眼科学
  • 霊長類研究
  • 生体力学工学

背景:

  • 近視は一般的な視覚障害であり、眼球の過度の軸性伸長を特徴とする。
  • 眼球剛性のような眼球の生体力学的特性を理解することは、近視発生の解明に不可欠である。
  • 以前の研究では眼球剛性に影響を与える要因が探求されてきたが、近視の霊長類モデルにおける直接的な生体評価は限られている。

研究 の 目的:

  • 実験的に誘発された近視が若いアカゲザルの眼球剛性に及ぼす影響を調査すること。
  • 形態剥奪近視眼とその対側の対照眼の眼球剛性を比較すること。

主な方法:

  • 8匹のアカゲザルに24日から150日齢まで単眼形態剥奪を適用した。
  • 屈折、軸長、および眼圧を2週間ごとに測定した。
  • 眼球剛性は、前房カニューレを使用して評価し、Friedenwaldの式を用いて計算した。

主要な成果:

  • 形態剥奪眼は、対照眼と比較して有意な軸性伸長と近視シフトを示した。
  • 形態剥奪眼と対照眼の間で、眼球剛性の係数に有意な差は見られなかった。
  • 軸長が増加するにつれて眼球剛性が低下する傾向が示唆されたが、統計的に有意ではなかった。

結論:

  • 若いアカゲザルにおける実験的近視誘発は、眼球剛性を有意に変化させることなく、軸性伸長と近視シフトをもたらす。
  • この研究は、統計的検出力が限られている可能性があるものの、眼球剛性に対する眼球サイズの潜在的な影響を強調している。
  • この研究は、霊長類モデルにおける眼球剛性の生体評価法を確立し、近視における将来の生体力学的研究への道を開くものである。